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Expression data from adult myocardium of ToF-PVR patients undergoing pulmonary valve replacement

ABSTRACT: Adult right ventricle from Tetralogy of Fallot patients undergoing pulmonary valve replacement vs right ventricle myocardium from unused donor hearts we used Microarray to determine whether there were differences in gene expression between these groups

ORGANISM(S): Homo sapiens

PROVIDER: GSE141955 | GEO | 2020/06/22

REPOSITORIES: GEO

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Investigation of TOF patient heart specimens

Project description:The protein BBLN with largely unknown function was identified in human right ventricular heart specimens from patients undergoing repair surgery for Tetralogy of Fallot (TOF). Proteins from heart specimens were solubilized and subjected to immuno-affinity enrichment with anti-CAMK2D-specific antibodies. Co-enriched proteins were separated by SDS-PAGE, and the protein band in the range of 8-14 kDa was cut and subjected to identification by nano-LC-ESI-MS/MS.

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Whole genome microarray gene expression profiling of right ventricular heart specimens from pediatric patients with Tetralogy of Fallot (TOF)

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