Genomics

Dataset Information

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RNA sequencing analysis revealed a distinct motor cortex transcriptome in spontaneously-recovered mice after stroke


ABSTRACT: The goal of this study is to elucidate the intrinsic changes in spontaneous recovery after stroke, by directly investigating the transcriptome of primary motor cortex in mice that naturally recovered after stroke. Overall design: Examination of gene expression in the primary motor cortex of spontaneously recovered (3) versus non-recovered (5) stroke mice

INSTRUMENT(S): Illumina HiSeq 4000 (Mus musculus)

ORGANISM(S): Mus musculus  

SUBMITTER: Michelle Cheng  

PROVIDER: GSE142152 | GEO | 2019-12-17

REPOSITORIES: GEO

Dataset's files

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GSE142152_cM1.txt.gz Txt
GSE142152_iM1.txt.gz Txt
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Publications


Background and Purpose- Many restorative therapies have been used to study brain repair after stroke. These therapeutic-induced changes have revealed important insights on brain repair and recovery mechanisms; however, the intrinsic changes that occur in spontaneously recovery after stroke is less clear. The goal of this study is to elucidate the intrinsic changes in spontaneous recovery after stroke, by directly investigating the transcriptome of primary motor cortex in mice that naturally reco  ...[more]