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Single-cell RNAseq profiling of dog primary mammary triple-negative breast cancer cells infected or not with a vaccinia virus deleted for the thymidine kinase gene

ABSTRACT: Dog breast cancer cells were infected at a multiplicity of infection of 5 for 6 houurs or mock-infected (Control) for 6 hours prior to analyses by single-cell RNA sequencing. The objective was to study the distribution of host cell and viral gene expression on the cancer cell population and to compare the effect of viral infection on these cells.

ORGANISM(S): Canis lupus familiaris

PROVIDER: GSE142184 | GEO | 2020/10/07

REPOSITORIES: GEO

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RNAseq profiling of dog primary mammary triple-negative breast cancer cells infected or not with a vaccinia virus deleted for the thymidine kinase gene

Project description:Dog breast cancer cells were infected at a multiplicity of infection of 5 for 6 hours or mock-infected (Control) for 6 hours prior to analyses by single-cell RNA sequencing. The objective was to study the distribution of host cell and viral gene expression.on the cancer cell population and to compare the effect of viral infection on these cells.

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Expression profiling of dog primary mammary triple-negative breast cancer cells infected or not with a vaccinia virus deleted for the thymidine kinase gene

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