Single cell hierarchy of the mouse vaginal epithelium

ABSTRACT: In this study, using genetic cell lineage tracing, vaginal organoids, targeted gene deletion and single cell sequencing approaches; we revealed a unique population of vaginal epithelial stem cells and provided evidence that canonical Wnt/b-catenin signaling is required for the proliferation and differentiation of these stem cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE142212 | GEO | 2019/12/18

REPOSITORIES: GEO