Pseudomonas aeruginosa core metabolism exerts a widespread growth-independent control on virulence

ABSTRACT: Gene expression analysis of highly vs. lowly pathogenic P. aeruginosa strains identifies many virulence factors and only a few metabolism genes related to virulence. Functional transcriptomics re-analysis of core metabolism at the pathway level, reveals amino-acid, succinate, citramalate, and chorismate biosynthesis and beta-oxidation as important for full virulence and expression of these pathways indicative of virulence in various strains.

ORGANISM(S): Pseudomonas aeruginosa

PROVIDER: GSE142464 | GEO | 2020/01/02

REPOSITORIES: GEO