Ventral midbrain-type neural stem/precursor cells (VM-NSCs) derived from human midbrain organoids as a stable source for treating symptoms of Parkinson’s disease

ABSTRACT: In this study, midbrain-like organoids were yielded from hPSCs to prepare cells used for PD therapy. Neural stem/precursor cells (NSCs) isolated from midbrain organoids (Og-NSCs) expanded stably and differentiated into mDA neurons, and an unprecedentedly high proportion express midbrain-specific factors.

ORGANISM(S): Homo sapiens

PROVIDER: GSE142505 | GEO | 2020/02/29

REPOSITORIES: GEO