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Microarray gene expression analysis of HNSCC- and BM- derived mesenchymal stromal cells

ABSTRACT: Head Neck Squamous Cell Carcinoma (HNSCC)- or Bone Marrow (BM)- derived mesenchymal stromal cells (MSC) were analyzed either resting or following stimulation with IFN-g and TNF-a cytokines.

ORGANISM(S): Homo sapiens

PROVIDER: GSE142816 | GEO | 2020/12/30

REPOSITORIES: GEO

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Cervical lymph node metastasis high metastatic HNSCC lines vs non-metastatic HNSCC lines

Project description:This study is the orthotopic nude mouse model of Head and neck squamous cell carcinoma (HNSCC).

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delta-Np63 loss of function study in the HNSCC cell line UT-SCC-74A

Project description:delta-Np63 is highly expressed in squamous cell carcinoma of the head and neck (HNSCC). To evaluate its function in HNSCC we depleted delta-Np63 by siRNAs in the HNSCC cell line UT-SCC-74A. The transcriptome was analysed by cDNA microarray.

2016-01-14 | E-MTAB-3670 | biostudies-arrayexpress

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Expression data of HNSCC cell lines in normoxia and hypoxia

Project description:Hypoxia has been linked to increased treatment resistance in many solid tumors, including head and neck squamous cell carcinoma (HNSCC). We aim to identify genes involved in hypoxia-mediated response to radiotherapy in HNSCC. We used microarrays to investigate the influence of hypoxia on the global gene expression in HNSCC.

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