Context-dependent IL-1 mRNA-destabilization by TTP prevents dysregulation of immune homeostasis

ABSTRACT: We report that TTP exhibits context-dependent target destabilisation and that such context-defined mRNA decay is essential for maintaining steady state IL-1 levels in the physiological range

ORGANISM(S): Mus musculus

PROVIDER: GSE143241 | GEO | 2020/06/23

REPOSITORIES: GEO