Genome wide anaylsis of transcriptome modifications in male mice exposed to tributyltin during development

ABSTRACT: Purpose: To identify alterations induced by developmental exposure to tributyltin at different stages of life Methods: Dams were treated with tributyltin during gestation and lactation in drinking water and pups were euthanized at different ages Results: We identified a number of changes in transcriptomic activity in 5 month, and ten month old pups after tributyltin exposure. Male animals exposed to tributyltin also developed fatty liver 5 months of age and adenomas of the liver at ten months of age.

ORGANISM(S): Mus musculus

PROVIDER: GSE143304 | GEO | 2020/02/24

REPOSITORIES: GEO