Cytomegalovirus subverts macrophage identity [Bone marrow-derived macrophages]

ABSTRACT: Macrophages, which populate barrier tissues already in the embryo, are primary targets for CMV. Upon infection macrophages undergo a morphological, immunophenotypic and metabolic transformation process with features of stemness, altered migration, enhanced invasiveness and provision of the cell cycle machinery to viral proliferation.

ORGANISM(S): Mus musculus

PROVIDER: GSE143446 | GEO | 2021/06/15

REPOSITORIES: GEO