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Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons

ABSTRACT: To examine the roles of the ADAR genes and the ERI-6/7 helicase in endogenous RNAi pathways, we sequenced small RNA of adr-1; adr-2; eri-6 mutants. We also analyzed the transcriptomes of these mutants using total RNAseq and mRNAseq. mRNAseq was done in mutants depleted for the RNAi factors drh-1 and nrde-3, or control RNAi

ORGANISM(S): Caenorhabditis elegans

PROVIDER: GSE143595 | GEO | 2020/01/14

REPOSITORIES: GEO

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The ERI-6/7 helicase acts at the first stage of an siRNA amplification pathway that targets recent gene duplications.

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Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons

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Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons.

Project description: Not available

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The ERI-6/7 helicase acts at the first stage of an siRNA amplification pathway that targets recent gene duplications.

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