The effect of ANGPTL3 mAb on liver transcriptomes in LDLR-deficient mice

ABSTRACT: Purpose: The goal of this study was to evaluate the effect of ANGPTL3 inhibition on liver transcriptomes in LDLR KO mice. Methods: Mice were treated once weekly for 3 weeks with 25mg/kg control mAb or ANGPTL3 mAb. Livers were harvested 6 days after the last mAb treatment. Results: ANGPTL3 inhibition had no major impact on hepatic gene expression.

ORGANISM(S): Mus musculus

PROVIDER: GSE143726 | GEO | 2020/07/05

REPOSITORIES: GEO