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Influence of the putative transcription factor ClbR and the thioesterase ClbQ on colibactin synthesis regulation and characterization of critical transcription start sites in Escherichia coli


ABSTRACT: By comparing the transcriptome profile upon deletion or overexpression of ClbR or ClbQ, we addressed the role of these proteins in regulation of colibactin expression. Our global screen indicates that ClbR is the key transcriptional activator of colibactin expression. In addition, we further investigated potential transcription start sites of the colibactin determinant.

ORGANISM(S): Escherichia coli

PROVIDER: GSE143807 | GEO | 2020/01/17

REPOSITORIES: GEO

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