Genome-wide maps of chromatin state in Pep2-CM4-treated and control lymphoma cells

ABSTRACT: We report the application of single-molecule-based sequencing technology for high-throughput profiling of RNAPII with promoters in mammalian cells. We performed ChIP sequencing with antibody to total RNAPII in Pep2-CM4-treated and control group. Inspection of multiple individual traces and global analyses showed that Pep2-CM4-treated cells globally reduced association of RNAPII with promoters.

ORGANISM(S): Homo sapiens

PROVIDER: GSE143865 | GEO | 2020/10/10

REPOSITORIES: GEO