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Distinct roles of PARP-1 and PARP-2 in c-Myc-driven B cell Lymphoma in mice

ABSTRACT: To study the implication of PARP-1 deficiency or PARP-2 deficiency in the development of c-Myc overexpression-induced B lymphomas, we have studied by RNAseq the gene expression profile in pre-B cells isolated from bone marrow of mice that overexpress c-Myc in their B lymphocytes (WT) and in those mice with PARP-1 (KO1) or PARP-2 (KO2) deficiency

ORGANISM(S): Mus musculus

PROVIDER: GSE144050 | GEO | 2021/12/31

REPOSITORIES: GEO

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