The profile of circular RNA in hypoxic exosomes from lung adenocarcinoma cell line

ABSTRACT: Hypoxia is a common feature of solid tumors and is associated with aggressiveness and poor prognosis of patients. Exosomes are involved in mediating cellular environment interactions. circRNAs are a class of non-coding RNAs (ncRNAs) broadly expressed in cells and exosomes. However, in lung adenocarcinoma tumor development, functions and regulatory mechanisms of exosomal circ-RNAs induced by hypoxia remain poorly understood.To further explore the differences in recombinant RNA expression in hypoxic and normoxic exosomes derived from lung adenocarcinoma cell line

ORGANISM(S): Homo sapiens

PROVIDER: GSE144053 | GEO | 2023/01/21

REPOSITORIES: GEO