Remodeling of Zn2+ Homeostasis Upon Differentiation of Mammary Epithelial Cells

ABSTRACT: Using mouse mammary epithelial cells as a model system, we investigated the remodeling of zinc homeostasis during differentiation induced by treatment with the lactogenic hormones cortisol and prolactin. RNA-Seq at different stages of differentiation revealed changes in global gene expression, including genes encoding zinc-dependent proteins and regulators of zinc homeostasis. Increases in mRNA levels of three zinc homeostasis genes,.

ORGANISM(S): Mus musculus

PROVIDER: GSE144160 | GEO | 2020/01/24

REPOSITORIES: GEO