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Single-cell RNA-seq analysis of microglial cells in demyelinated corpus callosum

ABSTRACT: CX3CR1-GFP mice were fed with cuprizone for 4 weeks to induce brain demyelination. The central and lateral parts of the corpus callosum (CC) were then separately dissected, dissociated and GFP+ microglial cells were isolated by FACS. 2133 migroglial cells from medial CC and 2304 cells from lateral CC were then processed for single-cell RNA-seq analysis. Single Cell RNA sequencing library were generated using the 10x Genomics Chromium Platform and sequenced on the Illumina Nextseq 500.

ORGANISM(S): Mus musculus

PROVIDER: GSE144202 | GEO | 2021/06/04

REPOSITORIES: GEO

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Single-cell RNA-seq analysis of subventricular zone-derived neural progenitors mobilized to demyelinated corpus callosum

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Project description:Single-cell RNA-seq analysis of microglial cells in demyelinated corpus callosum

| PRJNA603051 | ENA

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