PAF1 Drives Pancreatic Cancer Oncogenesis by Promoting Stemness via PHF5A/DDX3 Sub-complex (RNA-seq)

ABSTRACT: In this study, we established that PAF1 is critical for pancreatic tumorigenesis, and CSC-driven tumor maintenance because depletion of PAF1 resulted in significantly less tumor burden and reduction in CSC populations.

ORGANISM(S): Homo sapiens

PROVIDER: GSE144370 | GEO | 2020/01/29

REPOSITORIES: GEO