Epigenetic Targeting of the Warburg Effect by Inhibition of Histone-Deacetylases Leads to Activation of Oxidative Metabolism

ABSTRACT: FDA-approved global (panobinostat, vorinostat) and selective (romidepsin) histone-deacetylase (HDAC) inhibitors elicit metabolic reprogramming in concert with disruption of several Warburg-effect related super-enhancers

ORGANISM(S): Homo sapiens

PROVIDER: GSE144399 | GEO | 2020/01/29

REPOSITORIES: GEO