DGAT1 is a bona fide oncogene stimulating cell growth and suppressing oxidative stress while enabling fatty acid accumulation

ABSTRACT: Forced over-expression of dgat1a using the minicoopR system increased the rate of tumour formation in tp53m214K/m214k; mitfa-/-; nras G12D. This was through increased TOR signalling and alterations in key metabolic pathways.

ORGANISM(S): Danio rerio

PROVIDER: GSE144555 | GEO | 2023/01/30

REPOSITORIES: GEO