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RNA-seq of MV-4-11 or THP-1 cells treated with LSD1 inhibitor INCB059872

ABSTRACT: INCB059872 is a selective irreversible inhibitor of Lysine-Specific Demethylase 1 (LSD1) that is in phase 1 clinical trials in hematopoietic malignancies. LSD1 inhibition can induce differentiation of acute myeloid leukemia (AML), and here we have used RNA-seq to measure the transcriptional changes caused by INCB059872 in two AML cell lines.

ORGANISM(S): Homo sapiens

PROVIDER: GSE145106 | GEO | 2020/05/28

REPOSITORIES: GEO

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PRO-seq of THP-1 cells treated with LSD1 inhibitor INCB059872

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RNA-seq of murine megakaryocyte progenitor cells treated with LSD1 inhibitor INCB059872

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RNA-seq of MV-4-11 or THP-1 cells treated with LSD1 inhibitor INCB059872

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