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Identification of genes regulated by Foxc1, which is a host target of miR-138

ABSTRACT: In other parts of this study we identified Foxc1 as a host target of miR-138 and found that Foxc1 can promote herpes simplex virus-1 (HSV-1) replication. To understand the mechanisms of this function, we performed an RNAseq experiment comparing vector (pcDNA) and pFoxchuman transfected Neuro-2a cells. After transfection, these cells were infected with HSV-1 for 5 hours at an MOI of 1 to identify viral genes regulated by Foxc1 as well as host genes.

ORGANISM(S): Mus musculus Human alphaherpesvirus 1

PROVIDER: GSE145499 | GEO | 2020/04/27

REPOSITORIES: GEO

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