Effect of Flt3L and DNGR-1 on the biology of tumor-infiltrating type 1 dendritic cells

ABSTRACT: DNGR-1 is a dead cell-sensing receptor specifically expressed in type 1 conventional dendritic cells (cDC1s), but whether it plays a role in antitumor immunity remains unexplored. In our work we have explored the transcriptional profile of tumor-infiltrating cDC1s competent or deficient in DNGR-1,

ORGANISM(S): Mus musculus

PROVIDER: GSE145534 | GEO | 2021/05/19

REPOSITORIES: GEO