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Changes in global open chromatin structure caused by acute deletion of TERT in spermatogonial stem cells

ABSTRACT: To understand the catalytic activity-independent functions of TERT in global chromatin structure, we acutely deleted TERT in spermatogonial stem cell (SSC) populations in the testis, and performed ATAC-seq. We find significant global loss of open chromatin structure in TERT-deleted SSC populations.

ORGANISM(S): Mus musculus

PROVIDER: GSE145658 | GEO | 2024/07/11

REPOSITORIES: GEO

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Changes in global gene expression patterns caused by acute deletion of TERT in spermatogonial stem cells

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