Cycling stem cells regenerate the damaged intestinal epithelium upon irradiation

ABSTRACT: The intestinal epithelium undergoes DNA damage response, regenerative response and homeostasis after suffering irradiation. To understand the dynamic change of intestinal epithelium during the irrradiation recovery, we performed single cell RNA sequencing on irradiation-resistant +4 cells in homeostasis and its lineages at different time points after radiation.

ORGANISM(S): Mus musculus

PROVIDER: GSE145866 | GEO | 2020/06/07

REPOSITORIES: GEO