Expression data from RAW 264.7 macrophage

ABSTRACT: IFNg is a pro-inflammatory and pro-atherogenic cytokine that leads to macrophage activation. Adenosine has well-documented anti-inflammatory properties. We used microarrays to compare the global gene expression profile in mouse macrophages stimulated with IFNg alone and those cells treated with IFNg and adenosine. We determined that adenosine suppressed the expression of many IFNg-regulated pro-inflammatory cytokines, chemokines, and other pro-atherogenic genes. Keywords: treatment response

ORGANISM(S): Mus musculus

PROVIDER: GSE14612 | GEO | 2009/12/31

SECONDARY ACCESSION(S): PRJNA112311

REPOSITORIES: GEO