DYRK2 knockout mice exhibit fetal growth retardation

ABSTRACT: We generated DYRK2-deficient mice using the CRISPR/Cas9 genome editing method and demonstrated that loss of DYRK2 gene causes fetal growth retardation and neonatal lethality at birth. Total RNA from DYRK2-/- whole embryo was compared with those of WT mice by microarray.

ORGANISM(S): Mus musculus

PROVIDER: GSE146614 | GEO | 2020/04/27

REPOSITORIES: GEO