Genomics

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Local states of chromatin compaction in HepG2 cells


ABSTRACT: We reported chromatin compaction states within several nucleosomes in HepG2 cells. To assess the local compaction, fromaldehyde-treated chromatin was appled to fractionation via a sedimentation velocity cetrifugation. While less-crosslinked nucleosomes remained in upper fractions as open chromatin, well-crosslinked nucleosomes were sedimented to lower fractions as compact chromatin.

ORGANISM(S): Homo sapiens

PROVIDER: GSE146632 | GEO | 2020/03/10

REPOSITORIES: GEO

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