Next Generation Sequencing Facilitates Quantitative Analysis of ISL1 Regulated Transcriptomes

ABSTRACT: The goal of this study is to analyze the transcriptome profiling (RNA-seq) after ISL1 knockdown. The objective of this study is to elucidate the mechanisms of ISL1 in gastric carcinogenesis, RNA-Seq is performed in BGC823 cells with stable ISL1 knockdown. Comparison and identification of the candidate genes based on the intersection of RNA-seq showed that upregulated and downregulated genes had ISL1-bound regions.

ORGANISM(S): Homo sapiens

PROVIDER: GSE147006 | GEO | 2021/03/24

REPOSITORIES: GEO