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Gene expression in the F1 and F2 mouse hippocampus with intrauterine hyperglycemia exposure

ABSTRACT: Studies on human and animals suggest associations between gestational diabetes mellitus (GDM) with impaired cognitive performance in offspring. Using a mouse model of diabetes during pregnancy, we found that intrauterine hyperglycemia exposure resulted in memory impairment in both the first filial (F1) males and the second filial (F2) males from the F1 male offspring. The effects of intrauterine hyperglycemia exposure on F1 and F2 hippocampus gene expression were also examined.

ORGANISM(S): Mus musculus

PROVIDER: GSE147039 | GEO | 2021/08/25

REPOSITORIES: GEO

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Epigenetic reprogramming of sperm in F1 adult male mice with intrauterine hyperglycemia exposure

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Intrauterine hyperglycemia exposure per se altered metabolic functions in F2 offspring via reprogramming F1 PGCs

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Gene expression in the F1 and F2 mouse hippocampus with intrauterine hyperglycemia exposure

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