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Mechanistic understanding of the combined immunodeficiency in complete human CARD11 deficiency

ABSTRACT: From lymphoblastoid cell lines derived from two homozygous CARD11-deficient patients and two heterozygous parents of the first patient, we performed differential expression analysis, gene set enrichment, and pathway analyses by RNA-Seq to demonstrate impaired activation of critical immune pathways.

ORGANISM(S): Homo sapiens

PROVIDER: GSE147531 | GEO | 2021/04/09

REPOSITORIES: GEO

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Mechanistic understanding of the combined immunodeficiency in complete human CARD11 deficiency

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