Genomics

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Malignant Schwann cell precursors mediate intratumoral plasticity in human neuroblastoma [Array]

ABSTRACT: we used single-cell transcriptomics and genotyping arrays to characterize 17 neuroblastoma samples across different risk groups and genetic subsets.Fresh samples, obtained from surgical resections and core biopsies, were used for genome variation profiling. DNA extraction from neuroblastoma samples was performed using the DNeasy blood and tissue kit (Qiagen) according to the manufacturer’s protocol. DNA quality was assessed using the Tapestation platform (Agilent). SNP microarray analysis was performed using the Cytoscan HD Array (Affymetrix) and data was processed using the Chromosome Analysis Suite version 3.3.0.139.

ORGANISM(S): Homo sapiens

PROVIDER: GSE147773 | GEO | 2022/12/14

REPOSITORIES: GEO

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