Physiologic RNA Targets and Refined Sequence Specificity of Coronavirus EndoU

ABSTRACT: Coronavirus EndoU inhibits double-stranded RNA (dsRNA)-activated antiviral responses; however, it is unclear how this occurs because the physiologic RNA substrates of EndoU are unknown. In this study, we used Mouse Hepatitis Virus (MHV)-infected bone-marrow-derived macrophage (BMM) and cyclic phosphate cDNA sequencing to identify the RNA targets of EndoU

ORGANISM(S): Mus musculus

PROVIDER: GSE147852 | GEO | 2020/09/18

REPOSITORIES: GEO