Human immature neutrophils as a functional biomarker of systemic vascular pathologies

ABSTRACT: We used an ex vivo system of murine ER-Hoxb8 neutrophils that phenotypically and morphologically recapitulate neutrophil maturation stages during five days of in vitro culture in the presence of G-CSF. To investigate the development of the ROS system in neutrophils during their development, we compared transcriptomes of D0, D1, D3 and D5 Hoxb8 neutrophils.

ORGANISM(S): Mus musculus

PROVIDER: GSE147910 | GEO | 2020/09/15

REPOSITORIES: GEO