Project description:In order to further determine the je virus (JEV) infection in C57BL / 6 mice after its miRNA levels change, we use the Agilent micrornas chip as a platform, to detect the uninfected group (control group) and the experimental mouse total RNA, it is found that the miRNA levels decrease infection group, and picked out the ten changes obviously micrornas verification, the result is the same.
Project description:In order to further determine the changes in gene expression levels of Japanese encephalitis virus (JEV) C57BL / 6 mice after infection, we used the Agilent single-channel expression profile chip as a platform to detect the total brain tissue of mice in the uninfected (control) and experimental groups Compared with the control group, it was found that the gene expression levels of several mice in the experimental group were lower than those in the control group. We selected ten or so genes with significant changes for verification, and the results were consistent.