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Cadiac GATA-4 overexpression in vivo

ABSTRACT: The objective of the study was to find cardiac GATA-4 target genes by overexpressing GATA-4 transcription factor in the left ventricle by adenoviral gene transfer.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE14848 | GEO | 2009/12/01

SECONDARY ACCESSION(S): PRJNA112125

REPOSITORIES: GEO

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Cadiac GATA-4 overexpression in vivo

Project description:The objective of the study was to find cardiac GATA-4 target genes by overexpressing GATA-4 transcription factor in the left ventricle by adenoviral gene transfer. Gene expression profiles three days after GATA-4 gene transfer were compared with those of Lac Z –treated animals by screening Affymetrix Rat Expression Set 230_2.0 Arrays (there are 5 samples in both group). Strain:Sprague-Dawley; Gender, Male; Weight 250-300g; tissue, left ventricle.

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