Transcriptomics

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Single cell sequencing of murine CD4+ T cells from atherosclerotic aortas


ABSTRACT: We report the single cell transcriptome of CD4+ T cells from atherosclerotic aortas from ApoE-deficient mice that have been fed a western diet (WD) with aggravated atherosclerosis or with a standard chow diet (CD) with moderate atherosclerosis. We show that aortic T cells have a unique transcriptome with a mixed phenotype overlapping with T-regulatory and pathogenic T-helper type -1 and -17 cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE149069 | GEO | 2020/05/21

REPOSITORIES: GEO

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