Single-cell transcriptomic phenotyping combined with lineage tracing using paired B cell receptor repertoires identified both persistent antibody-secreting cell as well as memory B cell subsets after immunotherapy.
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ABSTRACT: Disease relevant B cells during post-rituximab (RTX)relapseemerge from the unsuccessfuldepletion of pre-existing B cell clones; single-celltranscriptomic phenotyping combined with lineage tracing using paired B cell receptor repertoires identified both persistent antibody-secreting cell as well as memory B cellsubsets.
ORGANISM(S): Homo sapiens
PROVIDER: GSE149133 | GEO | 2020/08/03
REPOSITORIES: GEO
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