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Genome-wide maps of EED and H3K27me3 binding genes in WT and HBL1 KO human induced pluripotent stem cells (hiPSCs).

ABSTRACT: We reported loss of HBL1 lnRNA promoted cardiogenesis and the interaction of HBL1-EED in hiPSCs. Here we used specific EED and H3K27me3 antibodies to pull down their binding genomic DNAs in hiPSCs, respectively, which let us know the potential genes regulated by HBL1-EED-H3K27me3 during cardiogenesis. 1% Input samples were collected from the same samples after chromatin shearing.

ORGANISM(S): Homo sapiens

PROVIDER: GSE149323 | GEO | 2021/06/10

REPOSITORIES: GEO

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The Central Role of EED in the Orchestration of Polycomb Group Complexes

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