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Genome-wide mRNA profiling of PBMCs from TB patients (TB) and healthy controls (HC)

ABSTRACT: Transcriptome microarray analysis was conducted to examine the gene expression profiling of PBMCs from active TBs and HCs. All 18,853 mRNAs in the microarray were used to draw a Heatmap of differential genes according to their expression levels. The genes that exhibited significant changes in expression were used for further validation. The TB group (n=15) exhibited a significantly different profile compared to the HC (n=15) group (Fig. 1a). A total of 1,595 differentially expressed mRNAs were identified between the two groups. Of these, 335 mRNAs were up-regulated (fold change ≥ 2), and 1,260 mRNAs were down-regulated (fold change ≥ 2).

ORGANISM(S): Homo sapiens

PROVIDER: GSE149458 | GEO | 2021/11/17

REPOSITORIES: GEO

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The FAK-Inhibitor BI 853520 exerts anti-tumor effects in breast cancer

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2019-07-19 | GSE116117 | GEO

Treatment of extracellular vesicles change gene expression in mesothelial cells

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Proteome and transcriptome analyses reveal key molecular differences between quality parameters of commercial-ripe and tree-ripe fig (Ficus carica L.)

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2019-03-22 | PXD009757 | Pride

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2019-07-31 | GSE14624 | GEO

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2015-05-25 | GSE68742 | GEO

Gene expression signatures in GIST-T1 cells transfected with a miR-335 mimic molecule

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2015-05-25 | E-GEOD-68742 | biostudies-arrayexpress

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2009-06-13 | E-GEOD-16473 | biostudies-arrayexpress

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2023-04-05 | GSE229000 | GEO

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