ND1 ex vivo gene therapy modulates the transcription of genes relevant to AD pathogenesis

ABSTRACT: Transcriptome analysis of human iPSC-derived hippocampal neurons overexpresing NEUROD1 We employed Affymetrix GeneChip microarray (Human Clariom D) to examine early transcriptomic changes in APP variant cells compared to control, upon viral delivery of ND1.

ORGANISM(S): Homo sapiens

PROVIDER: GSE149599 | GEO | 2020/04/30

REPOSITORIES: GEO