Transcriptional dynamics of iPSC differentiation into β cells revealed by single-cell RNA sequencing

ABSTRACT: Induced pluripotent stem cells can be differentiated in vitro into insulin-producing β cells. In this study we unveil the transcriptional dynamics of the differentiation and explain the heterogeneity of the final cell product, in comparison with β cells from organ donors.

ORGANISM(S): Homo sapiens

PROVIDER: GSE149613 | GEO | 2020/10/28

REPOSITORIES: GEO