Transcriptome-wide mapping of MARF1-bound mRNAs

ABSTRACT: To comprehensively identify MARF1-associated mRNAs, we performed iCLIP using engineered HEK293 cells stably expressing a doxycycline (Dox)-inducible FLAG-tagged MARF1 that lacks RNAse activity. Our iCLIP analysis of MARF1 in HEK293 cells identified 108 mRNAs bound by MARF1 and demonstrates that MARF1 binds to the majority of these mRNAs via their 3’UTRs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE149820 | GEO | 2020/06/16

REPOSITORIES: GEO