Cap analysis gene analysis (CAGE) of primary AML samples harbouring FLT3-ITD mutation (human)

ABSTRACT: The purpose of the experiment is to investigate transcriptome signatures of FLT3-ITD and TKD double mutations in AML and the underlying molecular mechanism of mutation-driven acquired resistance. We identify that 310 upregulated and 22 downregulated promoters in FLT3-ITD/D835 mutant AML cells compared to cells with FLT3-ITD (FDR<0.05).

ORGANISM(S): Homo sapiens

PROVIDER: GSE149962 | GEO | 2023/05/08

REPOSITORIES: GEO