IL-33 stimulates DCs to express SEMA4A

ABSTRACT: We hypothesized that IL-33 created Tc1-like condition in the modifying tumor microenvironment (TME). RNA-seq analysis of dendritic cells (DCs) showed the elevation of Il1rl1 and SEMA4A by IL-33, the latter of which was confirmed by qPCR, without significant upregulation of IL-12.

ORGANISM(S): Mus musculus

PROVIDER: GSE150110 | GEO | 2021/07/02

REPOSITORIES: GEO