Inducible smooth muscle specific deletion of Yap1/Wwtr1 in mouse

ABSTRACT: YAP and TAZ are transcriptional co-activators and downstream effectors of the Hippo pathway, which play crucial roles in organ size control and cancer pathogenesis. Genetic deletion of YAP/TAZ has revealed their critical importance for embryonic development of the heart, vasculature and gastrointestinal mesenchyme. The aim of this study was to determine the functional role of YAP/TAZ in adult smooth muscle cell in vivo.

ORGANISM(S): Mus musculus

PROVIDER: GSE150603 | GEO | 2020/10/28

REPOSITORIES: GEO