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Physical activity modulates macrophage phenotype in mammary tissue and inhibits tumor progression

ABSTRACT: We generated RNAseq results from the mammary tissues of mice from a 2 x 2 factorial design experiment (running wheels vs. control condition X clodronate liposomes vs. PBS liposomes) where EO771 mammary cancer cells had been engrafted in the mammary tissue for nascent tumor formation. RNAseq results were used to complete digital cytometry with the CIBERSORTx platform to analyze relative proportions of M1-like and M2-like macrophages in the mammary tissue.

ORGANISM(S): Mus musculus

PROVIDER: GSE150620 | GEO | 2020/05/15

REPOSITORIES: GEO

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