Transcriptomics

Dataset Information

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RNA-seq analysis of gestationally Cd-exposed hepatic transcriptome


ABSTRACT: We report the RNA-sequencing analysis of hepatic RNA isolated from CD-1 mice following gestational exposure to 500ppb CdCl2. We show that gestational Cd exposure alters the hepatic gene expression of female, but not male offspring in numerous pathways related to oxidative stress and mitochondrial dysfunction leading to endoplasmic reticulum stress that ultimately drives metabolic disruption of insulin signaling.

ORGANISM(S): Mus musculus

PROVIDER: GSE150679 | GEO | 2020/12/09

REPOSITORIES: GEO

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