Genome-wide DNA methylation data of 2 pairs of monozygotic twins clinically discordant for IgA nephropathy

ABSTRACT: Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis involves both genetic and environmental factors. DNA methylation, the most studied epigenetic modification, was shown to play a role in IgAN. In two pairs of IgAN-discordant monozygotic (MZ) twins, here we assessed genome-wide DNA methylation profiling and gene expression profiling in order to characterize DNA methylation changes in IgAN and their potential influences on gene expression.

ORGANISM(S): Homo sapiens

PROVIDER: GSE151456 | GEO | 2021/05/15

REPOSITORIES: GEO